Aref Khalkhali
PhD, Tarbiat Modares University
Title: Effect of new type of dietary supplementation on T3, T4, and TSH hormones in male rat lead acetate recipient
Biography
Biography: Aref Khalkhali
Abstract
Considering the increasing prevalence of thyroid gland diseases and the lack of proper treatment of this disease, the present study was conducted to investigate the effect of a new type of healthy and live food supplementation from Triticum on T3, T4, and TSH hormones in rats. In this research, healthy and live dietary supplementation were synthesized by a new and green route. This organic biomaterial was named NBS. The NBS healthy and live dietary supplementation had various vitamins, macro and micro molecules, and ingredients such as B1, B2, B3, B5, B6, B9, C, K, A, E, D, phosphorus, potassium, sulfur, magnesium, calcium, boron, iron, manganese, zinc, copper, omega-3, omega-6, omega-9, and etc. For induction of disease, the lead acetate was used in diet of rats. The mice received the new food supplementation for nutrition at therapeutic concentrations of 125, 250 and 500 mg/ kg body weight. According to the results, it can be concluded that food supplementation ation (healthy and live) causes the relative return of T3, T4 and TSH levels to normal. It was determined that the concentration of 500 mg/ kg has the most effective therapeutic effect on the condition of hypothyroidism. The new food supplementation (healthy and alive) has suitable therapeutic effect for treating abnormalities of thyroid parameters